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Why Plasma Therapy dropped?

After the eruption and spread of coronavirus in the world, people came to know the names of drugs like Hydroxychloroquine in first wave and Remdesivir in second wave. Treatment like plasma therapy also make in headlines to counter coronavirus in first wave. 

Kerala and Delhi governments gave importance to plasma therapy and made an appeal to coronavirus survivors to donate antibodies for covid patients. Now, Indian Council of Medical Research (ICMR) has decided to drop the use of convalescent plasma from the recommended guidelines of covid-19.


Plasma therapy extracts antibodies from coronavirus survivors and transfuses them to an infected patient. Experts had concerns over the efficacy of plasma therapy and its inappropriate use to treat patients. Last year, the ICMR, in one of the definitive clinical trials in the world, demonstrated that Convalescent Plasma Therapy (CPT) neither saved lives nor improved patient outcomes but was equivocal about it in public. Scientists have been warning against the irrational use of plasma therapy and have also been saying that it was ineffective.


Studies conducted in the US and UK are also pointing to wanton use of plasma therapy for causing the virus to mutate into more severe strains, which could further prolong the pandemic. The decision comes after India’s Covid-19 task force reviewed the effectiveness of plasma therapy on May 14th. Last year, there was a lot of hype and hope about plasma therapy as a cure of covid. Trials conducted on 11K volunteers across 40 hospitals revealed plasma therapy did not reduce a patient’s mortality rate.

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